Cyclosporine A impairs bone repair in critical defects filled with different osteoconductive bone substitutes
نویسندگان
چکیده
منابع مشابه
• Repair of Critical Femoral Defects in Rats by an Osteoconductive Synthetic Bone Graft
Filion, T; Li, X; Kreider, JM; Goldstein, SA; Ayers, DC; +Song, J University of Massachusetts Medical School, Worcester, MA; University of Michigan, Ann Arbor, MI +Senior author [email protected]; Filion and Li contributed equally INTRODUCTION: There is a pressing need for the development of more effective strategies to repair critical-sized bony defects in patients who have had volumetric ...
متن کاملOsteoconductive carriers for integrated bone repair
Successful bone repair is judged in achieving restitution of space and mechanical integrity, and in regaining function. When the biology or anatomy are insufficient to attain a full repair, therapeutic use of graft material has been used to omit compliance features such as strain tolerance, reduced stiffness, and attenuated strength, and instead promote primary or membranous-type bone formation...
متن کاملA Comparison of Mineral Bone Graft Substitutes for Bone Defects
Synthetic bone graft substitutes have evolved in response to the downsides of autograft and allograft. This article consolidates the literature regarding the use of mineral bone graft substitutes in the treatment of cavitary bone defects. No level I studies regarding their use in the treatment of bone tumors have been performed, but the clinical studies that have been published indicate that ca...
متن کاملThe Influence of Hyperbaric Oxygen Treatment on the Healing of Experimental Defects Filled with Different Bone Graft Substitutes
To assess potential effects of hyperbaric oxygen (HBOT) on artificial bone grafts, β - Tricalcium phosphate (β-TCP) and calcium phosphate coated bovine bone (CPCBB) substitutes were applied to standard bone defects in rat tibiae. The control defects were left empty. Half of the animals received 60 minutes of 2.4 atmosphere absolute (ATA) of HBOT. Rats were sacrificed at one, two and four weeks....
متن کاملRepair Process of Surgical Defects Filled with Autogenous Bone Grafts in Tibiae of Diabetic Rats
From a biological standpoint, the best material for reconstruction of bone defects is the autogenous bone graft. However, as tissue healing is affected under diabetic conditions, major changes might take place in the revascularization, incorporation, replacement and remodeling phases of the grafted area. The purpose of this study was to assess the bone healing process in surgical wounds prepare...
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ژورنال
عنوان ژورنال: Brazilian Oral Research
سال: 2020
ISSN: 1807-3107,1806-8324
DOI: 10.1590/1807-3107bor-2020.vol34.0007